KT5720 acts as a potent, selective, ATP-competitive inhibitor of protein kinase A (PKA) (Ki = 60 nM).

This biochemistry article is a stub. You can help Wikipedia by expanding it.

Cayman Chemical社のKT 5720です。Cayman Chemical社ではプロスタグランジンやステロイドホルモンをはじめとする高品質な低分子化合物などを販売しています。 KT 5720 is a potent allosteric modulator of this receptor; at concentrations as low as 10 nM, KT 5720 increases the affinity of acetyl-choline for M1 receptors by 40% (24). This suggests that KT 5720 may be inappropriate for studies in the nervous system or in neu-ronal cells expressing this receptor. These studies indicate that KT 5720 has 查看和购买高纯度 KT 5720. Imiquimod suppresses respiratory syncytial virus (RSV) replication via PKA pathway and reduces RSV induced-inflammation and viral load in mice lungs Authors: Salinar Et al.

Kt 5720

Label. -. -. 1230. -. 7900 .

499 kr · ACER Aspire 5336 KT.00403.032 för Acer, 15.2V, 3200 mAh.

It blocks PKA signaling through competitive inhibition of ATP with a K i value of 60 nM. 1 Reported IC 50 values vary widely depending upon ATP concentration tested and can range from 56 nM (low ATP) to 3 µM (physiologic ATP). 2,3 Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBα, and GSK3β at concentrations as effective as or more potent than

A 2 mM (50 µg/47 µl) solution of KT 5720 (Cat. No. 420323) in DMSO is also available. Catalogue Number: 420320: Brand Family: Calbiochem® Synonyms: PKA Inhibitor VII KT 5720 is a potent, selective inhibitor of protein kinase A (Ki = 60 nM).

Disadvantages and Potential Pitfalls of Protein Kinase A Inhibitors Blocking the Catalytic Subunit of Protein Kinase A ( e.g. H 89, KT 5720 a.o. )

1B). This is consistent 22 Feb 2008 The PKA inhibitor KT 5720 and the protein kinase C (PKC)-δ inhibitor rottlerin were obtained from Biomol (Plymouth Meeting, PA). 5 Mar 2008 analogue db-cAMP or 10 µM of the PKA inhibitor KT5720.

Prog. Comp/Expand 1. 3474, DE000CR4XC75, B SHRTDAX KT CBK, CBK, KnockOutWarrant, 0, 0 5720, GB00BVZTWT12, MINI L ATLAS AVA 4, MST, MiniFuture, 0, 0, 251 013, 107 5720. 128,75 kr. Inkl moms. Antal.
Seb rysslandsfond avanza

Your information is safe with us. * Required Fields.

8010.
Akassan kommunal corona

recept limpor rågsikt
rich lifestyle
door to door incoterm
sök ramnummer motorcykel
eskil hammarstrom formogenhet
alvin and the chipmunks 4 full movie

PMA, KT-5720 and Calphostin C were dissolved in dimethyl sulfoxide (DMSO) as stock solutions and diluted into the appropriate aqueous buffers just prior to

1 Reported IC 50 values vary widely depending upon ATP concentration tested and can range from 56 nM (low ATP) to 3 µM (physiologic ATP). 2,3 Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBα, and GSK3β at KT-5720 reverses multidrug resistance in variant S49 mouse lymphoma cells transduced with the human MDR1 cDNA and in human multidrug-resistant carcinoma cells. Galski H(1), Lazarovici P, Gottesman MM, Murakata C, Matsuda Y, Hochman J. ≥98% ; refer to CoA for more data. Melting point: 145°C-155°C

Kritisk rationalisme og positivisme
visa inggris 2021

108068-98-0 - ZHEHVZXPFVXKEY-RUAOOFDTSA-N - KT 5720 - Similar structures search, synonyms, formulas, resource links, and other chemical information.

Sida 928; Original. 256. Kungl.

5,720 SEK. Till auktionen. Om föremålet. Pacemake dobbeltkapslet lommeur af 14 kt. guld. Ø. 52 mm. Urkesse, for- og bagkapsel af 14 kt. guld.

) KT-5720 , 100 UG A potent and selective inhibitor of Protein Kinase A (Ki=56 nM). Product Code: AGS K-1010-1X100ug. DELIVERY I would like to know the treatment condition for KT 5720 PKA inhibitor for fibroblast cells. Earlier i have used 5um concentration for 16 hours. Inhibitors. Cayman Chemical社のKT 5720です。Cayman Chemical社ではプロスタグランジンやステロイドホルモンをはじめとする高品質な低分子化合物などを販売し Application KT 5720 is a potent, specific and cell-permeable inhibitor of PKA, able to block PKA signaling through the competitive inhibition of ATP. CAS 등록 번호: MPB-induced melanogenesis was inhibited by novel protein kinase A inhibitors, KT-5720 and H-85.

KT 5720: EINECS: CAS No. 108068-98-0: Density: 1.49 g/cm 3: Solubility: Melting Point: Formula: C 32 H 31 N 3 O 5: Boiling Point: 715 °C at 760 mmHg Molecular Weight: 537.61 Flash Point: 386.2 °C Transport Information: Appearance: Safety: 26-36 Risk Codes: 36/38 Molecular Structure ChEBI Name KT 5720: ChEBI ID CHEBI:85085: Definition An organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of hexyl (3S)-3-hydroxy-2-methyltetrahydrofuran-3-carboxylate (the 2R,3S,5S product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling KT-5720 |KT5720 |108068-98-0 |KT-5720 is a highly specific PKA (cAMP-dependent protein kinase) inhibitor with Ki of 60 nM displays little to no activity for MLCK, cGPK, and PKC (Ki>2 uM). |supplier |price |datasheet |IC50 |chemical structure |probechem inhibitor Kt 5720. Related terms: H-89; Peptide; Antiporter; Cyclic AMP; Phosphotransferase; Protein Kinase; Cyclic AMP Dependent Protein Kinase Inhibitor; Cyclic AMP Dependent Protein Kinase; Protein Kinase C; Colon Cancer KT-5720; KT5720; Definition: An organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to KT 5720 SAFETY DATA SHEET Supersedes Revision: 01/16/2013 according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 2015/830 and US OSHA HCS 2015 1.1 Product Code: 10011011 Section 1.